We are happy to announce the Rising Stars winners!
Holly Keir
Rising Star Winner (Bronchiectasis)
Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee (United Kingdom)
Title:
Sputum proteomics identifies mechanisms of disease severity and treatment response in bronchiectasis
Summary:
We conducted a series of UK and international studies to investigate the role of NETs in disease severity and treatment response in bronchiectasis. We found that NET-associated proteins are elevated in bronchiectasis sputum and are associated with disease severity, bacterial infection and mortality. Treatment response is linked to successfully reducing NET levels with intravenous antibiotic or macrolide therapies suggesting that NETs may be an important therapeutic target in bronchiectasis.
Jodie Schildkraut
Rising Star Winner (NTM – PD)
Department of Medical Microbiology, Radboudumc, Nijmegen (The Netherlands)
Title:
Dual RNA-Seq of M. avium identifies characteristic host-pathogen interactions
Summary:
In this study we characterize the host-pathogen interplay using dual RNA-sequencing of M. avium infected human monocyte derived macrophages. In addition, we investigate the effect of this interplay on the transcriptomic response to clarithromycin.
